Pepsin is an enzyme involved in protein digestion in the stomach. They work by neutralizing the stomach acid, which means that less acid develops in a person’s stomach.Īntacids also inhibit the production of pepsin in the body. AntacidsĪntacids are able to treat mild heartburn, indigestion, and mild GERD symptoms. These side effects include delirium, confusion, hallucinations, and slurred speech. People with renal impairment, those with hepatic impairment, and people over 50 years of age may also develop central nervous system side effects. Other mild side effects of H2 blockers include: However, in some rare instances, researchers have linked H2 blockers to cases of clinically apparent liver injury. People tend to tolerate these drugs well. H2 blockers are available over the counter or with a prescription. This reduces the amount of acid that they are able to secrete. They do this by binding to the histamine receptors. H2 blockers work by lowering the amount of hydrochloric acid in a person’s stomach. ![]() ![]() Having too much hydrochloric acid can cause GERD, along with a variety of other conditions. This causes the lining to make hydrochloric acid. Histamine is a chemical that stimulates cells in the stomach lining. These drugs can treat GERD, gastric or duodenal ulcers, gastric hypersecretion, and mild heartburn or indigestion. H2 blockers are sometimes called H2 receptor blockers or H2 receptor antagonists. There are a number of OTC GERD medications available, including: H2 blockers Share on Pinterest Andersen Ross/Getty Images This article will discuss some of the OTC treatments for GERD, how they work, and their side effects. There are a number of ways to treat the symptoms of GERD. ![]()
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